The study found no significant differences in morphokinetic parameters between male and female preimplantation embryos. In a retrospective cohort study conducted between March 2018 and June 2021 at two reproductive centers, researchers sought to determine whether there were differences in morphokinetic parameters between male and female preimplantation embryos. The study exclusively analyzed time-lapse data from 92 female and 83 male preimplantation embryos, which were derived from fresh oocyte donation and underwent intracytoplasmic sperm injection (ICSI). Only fresh elective single-embryo transfers on day 5 were assessed, and the sex of the embryo was confirmed at birth. Morphokinetic parameters were measured in hours post-insemination (hpi), and a two-tailed Student’s t-test was utilized to compare morphokinetics between embryo sexes, with P < 0.05 considered statistically significant. After excluding poor-quality preimplantation embryos, no significant differences were found in morphokinetic parameters between cycles resulting in female versus male live births. Therefore, the study concludes that there is no significant difference in morphokinetic parameters between male and female preimplantation embryos.
